Improving Neurodevelopmental Outcomes After Neonatal Herpes Simplex Virus Infection
نویسندگان
چکیده
منابع مشابه
Neonatal herpes simplex virus infection
Neonatal herpes simplex virus (HSV) infections may be caused by either herpes simplex virus type-1 (HSV-1) or herpes simplex virus type-2 (HSV-2). In the United States, HSV-2 is responsible for 75% of genital and neonatal infections, while HSV-1 causes the rest. HSV-1 more commonly affects the oropharynx, the eyes and the central nervous system.1,2 It is estimated that 20 to 30% of sexually act...
متن کاملRelapse of neonatal herpes simplex virus infection.
BACKGROUND Neonatal herpes simplex virus (HSV) infection is a severe disease with high mortality and morbidity. Recurrence of skin vesicles is common. OBJECTIVE To determine the features of relapse and identify the factors related to relapse. DESIGN Thirty two surviving patients with neonatal herpes virus infections were enrolled. All patients received acyclovir treatment. Clinical and viro...
متن کاملNeonatal herpes simplex infection.
Tremendous advances have occurred over the past 30 years in the diagnosis and management of neonatal herpes simplex virus (HSV) disease. Mortality in patients with disseminated disease has decreased from 85 to 29%, and that in patients with central nervous system (CNS) disease has decreased from 50 to 4%. Morbidity has been improved more modestly: the proportion of patients with disseminated di...
متن کاملDetection of Herpes Simplex Virus Infection in Cerebrospinal Fluid
ABSTRACT Background and Objective: Herpes simplex encephalitis is a life-threatening consequence of the central nervous system (CNS) infection with Herpes simplex virus (HSV). Although it is a rare disease, mortality rates reach 70% in the absence of therapy and only a minority of individuals can return to normal function. The aim of this study was to d...
متن کاملNeonatal herpes simplex virus infection in guinea pigs.
Neonatal herpes simplex virus (HSV) infection produces severe disease with unacceptable morbidity and mortality with current antiviral therapies. The effect of therapy with passive anti-HSV antibody and acyclovir was evaluated using a guinea pig model of neonatal HSV. Newborn animals were inoculated intranasally and treated with acyclovir (60 mg/kg/day) or antibody (or both), beginning on days ...
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ژورنال
عنوان ژورنال: Journal of Perinatology
سال: 2005
ISSN: 0743-8346,1476-5543
DOI: 10.1038/sj.jp.7211236